Abstract Background Glycolysis, a classic characteristic of cancer cells, can drive cancer progression by generating lactate, which play as a key immunosuppressive mediator.Currently, ubiquitin-specific proteases 5 (USP5) has been demonstrated to facilitate tumor cell survival in multiple myeloma (MM), whereas whether USP5 was involved in glycolysi
Failure Outdoor of a safety-critical system during mission execution can result in significant financial losses.Implementing mission abort policies is an effective strategy to mitigate the system failure risk.This research delves into systems that are subject to cumulative shock degradation, considering uncertainties in shock damage.To account for
This paper establishes nonlinear dynamic equation based on the consideration of elastic deformation of Napkin Holder shaft which happens in gear meshing process.In addition, the stiffness incentive, error incentive and external incentives caused by eccentric phenomenon during the process are analysed.The Newmark algorithm is also been used.Then the
Scheduling decisions for concurrent emergency response (CER) across multiple disaster sites presents numerous difficulties.The main challenge is to minimize human casualties while taking into account the rationality of resource allocation across different disaster sites.This paper establishes a joint scheduling model for emergency vehicles on freew